A lecture on key technologies and strategies for photodynamic treatment of acne by Wang Xiuli

18-11-2020

        Wang Xiuli, Chief Physician of Shanghai Dermatology Hospital, currently Director of Institute of Photomedicine, Tongji University School of Medicine, Director of International Photodynamic Association, Chief Expert of Photodynamic Therapy Research Center of Chinese Medical Association Dermatology Branch, etc.

        Today we invite director Wang Xiuli to explain to us the key technologies and strategies of photodynamic treatment of acne,The following is the main content of her lecture:

         Acne vulgaris is a common skin disease of adolescents. More than 90% of adolescents have been troubled by acne. About half of acne patients have scars, pigmentation and other sequelae. Moderate to severe acne affects appearance, tends to leave permanent scars, affects physical and mental health, and even causes depression and social difficulties.

acne

         For the treatment of severe acne, the first-line treatment in domestic and foreign guidelines is the use of tretinoin drugs. It has many effects and very good effects, but its side effects cannot be ignored. For example, its teratogenicity, used with caution during childbearing age, affects bone development, and used with caution during development, the impact on liver function and blood lipids, the most important thing is that its treatment course is longer: 6-12 months. With antibiotics for acnebecause of drug resistance, gastrointestinal reactions, and liver and kidney function, so its treatment period is relatively long: 2-3 months. Therefore, the treatment of acne with quick and good effect is photodynamic therapy. 

photodynamic-therapy

         Wang Xiulis team has used photodynamic therapy to treat acne for more than ten years. The photodynamic therapy mechanism requires light source and photosensitizer ALA. After the cells produce singlet oxygen, they need to be irradiated with light. Kernels equipment is use red light, which is wangxiuli teams favorite device.especially KN-7000D.it has 1820 pieces high power LEDs.Seven kinds of light combinations (red, blue, yellow, green, red+blue, red+yellow, red+infrared), High intensity lights output Under irradiation, singlet oxygen can be generated to Kill propionibacterium acnes in sebaceous gland cells and hair follicles.

PDT

          Two of the four articles cited in the 2016 American JAAD Acne Guidelines are from China. The article said: The status of photodynamic therapy in the world is very clear. Of all the laser and phototherapy treatments for acne, PDT is the most evidence. Adequate treatment.

More than 90% of the skin lesions in one week after photodynamic treatment of acne were completely resolved in the clinic more than ten years ago. After six months of three treatments, basically no skin lesions recurred.


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